The debug symbols are only part of the generated ELF files,
they are stripped from the .bin and .hex files.
So there should be no disadvantage of always generating it.
Before:
52456 Pinecil_EN.bin
81700 Pinecil_EN.elf
140759 Pinecil_EN.elf.map
147554 Pinecil_EN.hex
After:
52456 Pinecil_EN.bin
650556 Pinecil_EN.elf
191974 Pinecil_EN.elf.map
147554 Pinecil_EN.hex